Conservative adjudication resolves 21 of 110 material–axis pairs; 89 stay explicit uncertainty

Asked (summary)

Project ATLAS / ASTRA — a Keenable-only independent primary-authority review, search date 14 September 2026: research the ten exact cosmetic materials from scratch across exactly eleven safety & usage axes, preserving exact identity boundaries, using primary authorities, and returning evidence-grounded ingredient-level decisions without inferring product concentrations.

The evidence base is 67 authority findings across 10 source hosts, gathered on 14 September 2026, covering all ten catalog materials crossed with eleven safety-and-usage axes (110 cells). 60 findings are exact-INCI matches; 7 synonym or broader-group records are retained only to keep identity exclusions auditable and are never treated as direct evidence. CIR subdomains supply 40 of 67 findings, so the review is authority-concentrated, though independent EU, Canadian, ECHA, EPA, FDA and NCBI records are present; no single URL backs more than half the rows. Units are as stated by each source; no product concentration was inferred.

Ten materials by eleven axes

Conservative colors: hover or tap a cell for the exact basis. Yellow is not a hazard call — it means no exact-material primary-authority assessment directly closes the endpoint.

Lower concern — exact-material favorable evidence (15) Conditional restriction (5) Elevated endpoint concern (1) Explicit uncertainty — unresolved (89)

Findings the grid cannot say alone

Diethylhexyl Butamido Triazone is the one material without a favorable general-safety conclusion: its EU CosIng identity and Annex VI UV-filter maximum of 10% are verified, but no primary-authority safety opinion was located that closes general safety. ec.europa.eu

Tetrasodium EDTA carries the review's only elevated endpoint: an EU harmonised classification of harmful if swallowed and causes serious eye damage; Canada's screening found it not harmful at current Canadian exposure levels — a conclusion scoped to those exposures. echa.europa.eu

Caprylyl Methicone's exact-material oral study reported no adverse fertility, maternal, birth or fetal outcomes with a NOAEL above 1000 mg/kg bw/d, yet its cosmetic conclusion stays conditional: formulate non-irritating, with an unresolved airbrush-inhalation gap. cir-safety.org

Identity is a live variable, not a formality: castor oil spans raw, dehydrated, hydrogenated and ricinoleate records; the borosilicate is a glass with 0.001–33% reported use; the copolymer's clearance hinges on residual-monomer controls and guar's on heavy-metal and pesticide limits. cir-safety.org

Where the evidence comes from

Finding rows per source host — 67 rows, 10 hosts. CIR subdomains together hold 40 rows.

Evidence table, grouped by exact catalog material

All 67 authority findings. Non-exact identity matches (synonym, broader group) are flagged and support identity exclusions only.

Material label as sourced	Authority	Endpoint	Conclusion	Date	Identity	Source

Method: 67 primary-authority finding rows across 10 source hosts, collected 14 September 2026 for a Keenable-only review of ten exact cosmetic materials by eleven safety & usage axes (110 cells; 21 resolved, 89 explicit uncertainty). Grid colors are conservative adjudications of the sourced conclusions; doses and units are as stated by each source and no product concentration was inferred. Locator, dose and test-system details were cut from the table for space; conclusions are truncated to 220 characters.

This report was generated automatically by Keenable SELECT at a user's request, from publicly available web sources linked herein. Keenable does not review, verify, or endorse its contents and makes no representation as to accuracy, completeness, or timeliness; AI-based extraction may contain errors. Nothing in this report is investment, legal, financial, or other professional advice. All trademarks and referenced content remain the property of their respective owners; no affiliation or endorsement is implied. To report an error, rights concern, or request removal: legal@keenable.ai.