276 hazard-ratio estimates from vitamin D randomized trials, concentrated in a handful of mega-trials

Asked:

Find me all RCTs for vitamin D. In the table, report study name, paper name, outcome measure, HR, CI,

A broad live-web systematic search (2026-09-04) for randomized vitamin D supplementation trials reporting at least one hazard ratio with a confidence interval found 276 estimate rows across 20 extracted trial-name labels — some labels are aliases or ancillary studies of the same parent trial, so they are not 20 independent RCTs. Each row is one reported HR estimate, preserved exactly as extracted.

Reported HR estimates found, by trial label

Bar length = number of extracted HR rows per label — a count of published estimates, not trial size or quality. Hover a bar for papers and outcomes.

The Women's Health Initiative family contributes the most estimates: 88 HR rows across 7 papers under the main WHI label, plus 27 more under its calcium-plus-vitamin-D (CaD) arm label. pmc.ncbi.nlm.nih.gov

VITAL is the most published trial here — 12 papers with 57 HR rows over 32 distinct outcomes, plus ancillary labels VITAL-T2D and VITAL-DEP. pmc.ncbi.nlm.nih.gov

The most extreme point estimate is STURDY's frailty result — HR 0.22 (0.05–0.97), a small-event secondary analysis reported alongside a slow-gait HR of 1.58. link.springer.com

D-Health reported a myocardial infarction HR of 0.81 (0.67 to 0.98) while its overall major-cardiovascular-events HR of 0.91 crossed 1. vitamindwiki.com

Full evidence table

Every extracted estimate row. Filter by trial label or search papers and outcomes; click the HR header to sort. HR and CI are shown exactly as extracted.

Trial label	Paper	Outcome measure	HR ▾▴	CI	Source

Method: broad live-web systematic search conducted 2026-09-04. Inclusion: randomized vitamin D assignment and a reported hazard ratio with confidence interval; trials reporting only RR, OR, IRR, rate ratio, or mean differences are necessarily absent. 276 rows, 20 trial-name labels after semantic normalization (some are aliases or ancillary studies of the same parent trial), 39 distinct paper titles. Rows include primary, secondary, subgroup, sensitivity and ancillary analyses exactly as reported; calcium co-interventions are included where the randomized arm assigned vitamin D. Automated extraction can retain duplicate analytic variants or imperfect trial aliases. Not a regulatory-grade exhaustive bibliographic review.

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